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Effects of 10 to 30 years of lithium treatment on kidney function

Overview of attention for article published in Journal of Psychopharmacology, March 2015
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (95th percentile)
  • Good Attention Score compared to outputs of the same age and source (72nd percentile)

Citations

dimensions_citation
39 Dimensions

Readers on

mendeley
57 Mendeley
citeulike
1 CiteULike
Title
Effects of 10 to 30 years of lithium treatment on kidney function
Published in
Journal of Psychopharmacology, March 2015
DOI 10.1177/0269881115573808
Pubmed ID
Authors

Harald Aiff, Per-Ola Attman, Mattias Aurell, Hans Bendz, Bernd Ramsauer, Staffan Schön, Jan Svedlund

Abstract

Long-term lithium treatment is associated with end-stage renal disease, but there is little evidence of a clinically significant reduction in renal function in most patients. We previously found that 1.5% of people who took lithium from the 1960s and 1970s developed end-stage renal disease; however, none of the patients who started after 1980 had end-stage renal disease. Here we aimed to study the prevalence and extent of kidney damage during the course of long-term lithium treatment since 1980. We retrieved serum lithium and creatinine levels from 4879 patients examined between 1 January 1981 and 31 December 2010. Only patients who started their lithium treatment during the study period and had at least 10 years of cumulative treatment were included. The study group comprised 630 adult patients (402 women and 228 men) with normal creatinine levels at the start of lithium treatment. There was a yearly increase in median serum creatinine levels already from the first year of treatment. About one-third of the patients who had taken lithium for 10-29 years had evidence of chronic renal failure but only 5% were in the severe or very severe category. The results indicate that a substantial proportion of adult patients who are treated with lithium for more than a decade develop signs of renal functional impairment, also when treated according to modern therapeutic principles. Our results emphasise that lithium treatment requires continuous monitoring of kidney function.

Twitter Demographics

The data shown below were collected from the profiles of 5 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 57 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 2%
New Zealand 1 2%
Unknown 55 96%

Demographic breakdown

Readers by professional status Count As %
Researcher 10 18%
Student > Master 7 12%
Student > Bachelor 7 12%
Student > Doctoral Student 6 11%
Other 6 11%
Other 17 30%
Unknown 4 7%
Readers by discipline Count As %
Medicine and Dentistry 30 53%
Psychology 6 11%
Nursing and Health Professions 5 9%
Social Sciences 2 4%
Computer Science 2 4%
Other 7 12%
Unknown 5 9%

Attention Score in Context

This research output has an Altmetric Attention Score of 38. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 31 May 2018.
All research outputs
#638,580
of 17,036,910 outputs
Outputs from Journal of Psychopharmacology
#155
of 1,648 outputs
Outputs of similar age
#11,029
of 227,154 outputs
Outputs of similar age from Journal of Psychopharmacology
#10
of 37 outputs
Altmetric has tracked 17,036,910 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 96th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,648 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 24.3. This one has done particularly well, scoring higher than 90% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 227,154 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 95% of its contemporaries.
We're also able to compare this research output to 37 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 72% of its contemporaries.